Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here. See also 2018 N. Hosseinichimeh Plos ONE article for rumination focussed SD simulation

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here

Additional of glucagon hormone action to control glucose homeostasis

Overview of theory from Progress in Biophysics & Molecular Biology Special Issue 2016 From the century of the genome to the century of the organism: New theoretical approaches paper on organization. See example1 insight and example 2 insight Compare with Bogdanov (click tag)

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See IM-587 for Addition of Glucagon

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here

WIP for Nutrition and the first 1000 days

WIP representation of thinking feeling acting and interacting

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here. See also 2018 N. Hosseinichimeh Plos ONE article for rumination focussed SD simulation

Minimal model of glucose kinetics insight as a physiology circuit  and the more general secrete and grow notif from Uri Alon's System Medicine added. The circuits are then expressed in System Dynamics maps which distinguish between links and flows and add both where required

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here. See also 2018 N. Hosseinichimeh Plos ONE article for rumination focussed SD simulation

Protein conformance change based on Ed Gallaher and Jim Rogers 2021 Forrester Award Lecture ISDC

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

A simple glucose regulation causal loop diagram taken from Richard O. Foster, 1970: The Dynamics of blood sugar regulation, MSc thesis, MIT Dept of Electrical Engineering, available on the MIT System Dynamics Group Literature Collection and in the MIT Electronic Libraries. See IM-587 for Addition of Glucagon

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here. See also 2018 N. Hosseinichimeh Plos ONE article for rumination focussed SD simulation

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.

Double loop PCT IM-9007 extended to show hierarchical PCT and goal conflict psychotherapy. A simulation structure for IM-233044  See also a Suicide crisis and PCT IM-173189  simulation structure

Based on Psychological Medicine Dec 2015 article Depression as a systemic syndrome: mapping the feedback loops of major depressive disorder by A. K. Wittenborn, H. Rahmandad, J. Rick and N. Hosseinichimeh, mentioned here. See also 2018 N. Hosseinichimeh Plos ONE article for rumination focussed SD simulation

Physiology based insight to compare the energy balance and carbohydrate insulin models described in Nature Metabolism Obesity Causal Model Differences 2024 article See also Speakman and Hall's 2021 science article and insight and Stock flow Comparisons insight

Created in James Madison University's ISAT 341 Simulation and Modeling course by Joseph Straub and Andrew Funkhouser. Based on Mark Heffernan's Glucose-Insulin Insight Maker

Glucose Insulin Model Info:

Translated from Hormone.stm in Dynamic Modeling in the Health Sciences James L hargrove, Springer 1998, Ch 24 p255-261, by Mark Heffernan.